Synthesis and Characterization of Some New Cu(II), Ni(II) and Zn(II) Complexes with Salicylidene Thiosemicarbazones: Antibacterial, Antifungal and in Vitro Antileukemia Activity

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dc.contributor.author Pahonțu, Elena
dc.contributor.author Fala, Valeriu
dc.contributor.author Gulea, Aurelian
dc.contributor.author Poirier, Donald
dc.contributor.author Tapcov, Victor
dc.contributor.author Rosu, Tudor
dc.date.accessioned 2016-10-26T08:43:18Z
dc.date.available 2016-10-26T08:43:18Z
dc.date.issued 2013
dc.identifier.citation GULEA, Au., TAPCOV, Vl. et al. Synthesis and characterization of some new Cu(II), Ni(II) and Zn(II) complexes with salicylidene thiosemicarbazones:antibacterial, antifungal and in vitro antileukemia activity. In: Molecules. 2013, Vol.18, Issue 8, pp.8812-8836 en
dc.identifier.issn 1420-3049
dc.identifier.uri http://dspace.usm.md:8080/xmlui/handle/123456789/890
dc.description.abstract Thirty two new Cu(II), Ni(II) and Zn(II) complexes (1–32) with salicylidene thiosemicarbazones (H2L1–H2L10) were synthesized. Salicylidene thiosemicarbazones, of general formula (X)N-NH-C(S)-NH(Y), were prepared through the condensation reaction of 2-hydroxybenzaldehyde and its derivatives (X) with thiosemicarbazide or 4-phenylthiosemicarbazide (Y = H, C6H5). The characterization of the new formed compounds was done by 1H-NMR, 13C-NMR, IR spectroscopy, elemental analysis, magnetochemical, thermoanalytical and molar conductance measurements. In addition, the structure of the complex 5 has been determined by X-ray diffraction method. All ligands and metal complexes were tested as inhibitors of human leukemia (HL-60) cells growth and antibacterial and antifungal activities. en
dc.language.iso en en
dc.publisher Molecular Diversity Preservation International (MDPI) en
dc.subject copper en
dc.subject nickel en
dc.subject zinc complexes en
dc.subject thiosemicarbazones en
dc.subject antimicrobial activity en
dc.subject antileukemia en
dc.title Synthesis and Characterization of Some New Cu(II), Ni(II) and Zn(II) Complexes with Salicylidene Thiosemicarbazones: Antibacterial, Antifungal and in Vitro Antileukemia Activity en
dc.type Article en


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