SYNTHESIS, CHARACTERIZATION, CRYSTAL STRUCTURE AND ANTIMICROBIAL ACTIVITY OF COPPER(II) COMPLEXES WITH THE SCHIFF BASE DERIVED FROM 2-HYDROXY-4-METHOXYBENZALDEHYDE

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dc.contributor.author Pahonțu, Elena
dc.contributor.author Ilieș, Diana-Carolina
dc.contributor.author Shova, Sergiu
dc.contributor.author Paraschivescu, Codruța
dc.contributor.author Badea, Mihaela
dc.contributor.author Gulea, Aurelian
dc.contributor.author Roșu, Tudor
dc.date.accessioned 2016-04-05T10:31:50Z
dc.date.available 2016-04-05T10:31:50Z
dc.date.issued 2015
dc.identifier.citation PAHONȚU, E., ILIEȘ, D:-C., SHOVA, S. PARASCHIVESCU, C., BADEA, M., GULEA, A., ROȘU, T. Synthesis, characterization, crystal structure and antimicrobial activity of copper(ii) complexes with the schiff base derived from 2-hydroxy-4-methoxybenzaldehyde. In : Molecules. 2015, 20(4), pp.5771-5792 en
dc.identifier.issn 1420-3049
dc.identifier.uri http://dspace.usm.md:8080/xmlui/handle/123456789/582
dc.identifier.uri http://www.mdpi.com/1420-3049/20/4/5771
dc.description.abstract A novel Schiff base, ethyl 4-[(E)-(2-hydroxy-4-methoxyphenyl)methylene-amino]benzoate (HL), was prepared and structurally characterized on the basis of elemental analyses, 1H NMR, 13C NMR, UV-Vis and IR spectral data. Six new copper(II) complexes, [Cu(L)(NO3)(H2O)2] (1), [Cu(L)2] (2), [Cu(L)(OAc)] (3), [Cu2 (L)2Cl2(H2O)4] (4), [Cu(L)(ClO4)(H2O)] (5) and [Cu2(L2S)(ClO4)(H2O)]ClO4·H2O (6) have been synthesized. The characterization of the newly formed compounds was done by IR, UV-Vis, EPR, FAB mass spectroscopy, elemental and thermal analysis, magnetic susceptibility measurements and molar electric conductivity. The crystal structures of Schiff base and the complex [Cu2(L2S)(ClO4)(H2O)]ClO4·H2O (6) have been determined by single crystal X-ray diffraction studies. Both copper atoms display a distorted octahedral coordination type [O4NS]. This coordination is ensured by three phenol oxygen, two of which being related to the µ-oxo-bridge, the nitrogen atoms of the azomethine group and the sulfur atoms that come from the polydentate ligand. The in vitro antimicrobial activity against Escherichia coli ATCC 25922, Salmonella enteritidis, Staphylococcus aureus ATCC 25923, Enterococcus and Candida albicans strains was studied and compared with that of free ligand. The complexes 1, 2, 5 showed a better antimicrobial activity than the Schiff base against the tested microorganisms. en
dc.language.iso en en
dc.publisher MDPI AG en
dc.subject Schiff bases en
dc.subject copper(II) complex en
dc.subject crystal structure en
dc.subject EPR spectra en
dc.subject antimicrobial activity en
dc.title SYNTHESIS, CHARACTERIZATION, CRYSTAL STRUCTURE AND ANTIMICROBIAL ACTIVITY OF COPPER(II) COMPLEXES WITH THE SCHIFF BASE DERIVED FROM 2-HYDROXY-4-METHOXYBENZALDEHYDE en
dc.type Article en


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