Abstract:
The numerous scientific data regarding historical and biological aspects of transformation of wild brown rat in laboratory animal are summarized in the review. A special consideration was given to the influence of anthropogenic factor which favored the increase of animals’ ethological plasticity. Relying on the analysis of neuromediators and neuroendocrine changes by rats’ domestication a supposition about the peculiarities of stress infl uence upon physiological functions by albino rats is made.
