SPECTROPHOTOMETRIC STUDIES OF SANGUINARINE- Β - CYCLODEXTRIN COMPLEX FORMATION

Bratu, Ioan; Boldescu, Veaceslav; Duca, Gheorghe; Kacso, Irina

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dc.contributor.author	Boldescu, Veaceslav
dc.contributor.author	Kacso, Irina
dc.contributor.author	Bratu, Ioan
dc.contributor.author	Duca, Gheorghe
dc.date.accessioned	2018-03-26T12:47:38Z
dc.date.available	2018-03-26T12:47:38Z
dc.date.issued	2008
dc.identifier.citation	BOLDESCU, V., KACSO, I., et al. In: Cemistry Journal of Moldova. 2008, nr.1, pp. 85-88. ISSN 1857-1727.	en
dc.identifier.issn	1857-1727
dc.identifier.uri	http://dspace.usm.md:8080/xmlui/handle/123456789/1716
dc.description.abstract	The main aim of this study was to investigate the infl uence of pH and the presence of hydrophilic polymer polyvinylpyrrolidone on the formation of sanguinarine-β-cyclodextrin (SANG-β-CD) inclusion complex. Spectrophotometric studies of the SANG-β-CD systems in the presence and without 0.1 % PVP at the pH 5.0 did not show any evidence of the complex formation. However, the same systems showed several obvious evidences at the pH 8.0: the hyperchromic and the hypochromic effects and the presence of the isosbestic point in the region of 200 – 210 nm. The association constants calculated by three linear methods: Benesi-Hildebrand, Scott and Scatchard, were two times higher for the systems with addition of 0.1% PVP than for the systems without it.	en
dc.language.iso	en	en
dc.publisher	Academia de Știinițe a Moldovei	en
dc.subject	sanguinarine	en
dc.subject	β -cyclodextrin	en
dc.subject	inclusion complex	en
dc.subject	UV-vis spectrophotometry	en
dc.subject	association constant	en
dc.title	SPECTROPHOTOMETRIC STUDIES OF SANGUINARINE- Β - CYCLODEXTRIN COMPLEX FORMATION	en
dc.type	Article	en