ANALYSIS OF HUMAN URINARY STONES IN REPUBLIC OF MOLDOVA IN 2015-2023 BY INFRARED SPECTROSCOPY

Abstract

The method of Fourier transform infrared attenuated total reflectance (aTR FT-IR) spectroscopy is perspective to use for studying the chemical composition of urinary stones resulting from urolithiasis. 270 urinary stones of patients living in the territory of the Republic of Moldova were investigated. The results of stone composition can provide valuable information for the diagnosis, treatment and recurrence prevention of urolithiasis. The most common are oxalate stones (70%), uric acid (27%), phosphates (23%), struvite (4.9%). Carbonates (0.4%), cystine (1.5%), brushite (1.1%) were only rarely diagnosed. a spectral database of urinary stones of mixed type and in pure form was compiled, the spectra of which were obtained by aTR FT-IR spectroscopy method. The frequencies of absorption of functional groups and anions of chemical components of urinary stones were identifed, according to which stones were identifed. It has been shown that the IR spectra recorded using the aTR FT-IR accessory can be successfully used to study the composition of urinary stones along with the IR transmission spectra in KBr pellets.