dc.contributor.author |
Ciumacov, Iurie |
|
dc.contributor.author |
Graur, Vasilii |
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dc.contributor.author |
Ulchina, Ianina |
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dc.contributor.author |
Smaglii, Vadim |
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dc.contributor.author |
Gulea, Aurelian |
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dc.contributor.author |
Garbuz, Olga |
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dc.contributor.author |
Țapcov, Victor |
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dc.date.accessioned |
2023-10-23T09:02:18Z |
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dc.date.available |
2023-10-23T09:02:18Z |
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dc.date.issued |
2022 |
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dc.identifier.citation |
CIUMACOV, Iurie, GRAUR, Vasilii , ULCHINA, Ianina, SMAGLII, Vadim, GULEA, Aurelian, GARBUZ, Olga, ȚAPCOV, Victor . Crystal structures of [N′-(2- oxidobenzylidene)-N-(prop-2-en-1-yl carbamohydrazonothioato(2-)](1,10- phenanthroline)copper and [N′-(2- oxidobenzylidene)-N-(prop-2-)- en-1-yl)- carbamohydrazonothioato(2-)](2,2′- bipyridine)copper hemihydrates. În: Journal of Structural Chemistry, 2022, nr. 6(63), pp. 905-913. ISSN 0022-4766 |
en |
dc.identifier.issn |
0022-4766 |
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dc.identifier.uri |
http://dspace.usm.md:8080/xmlui/handle/123456789/11416 |
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dc.identifier.uri |
https://doi.org/10.1134/S0022476622060075 |
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dc.description.abstract |
The crystal structures and biological properties of [N′-(2-oxidobenzylidene)-N-(prop-2-en-1-yl)-carbamohydrazonothioato(2-)](1,10-phenanthroline)copper hemihydrate [Cu(1,10-Phen)(L)]·0.5H2O (I) and [N′-(2-oxidobenzylidene)-N-(prop-2-en-1-yl)-carbamohydrazonothioato(2-)](2,2′-bipyridine)copper hemihydrate [Cu(2,2′-BPy)(L)]·0.5H2O (II), where Н2L is 2-(2-hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide, are determined. The asymmetric unit of the unit cell in the crystal structures of I and II contains a copper complex with bidentate amine and a ligand coordinated by the azomethine nitrogen atom, the deprotonated phenolic oxygen atom, and the sulfur atom in the thiol form. The coordination polyhedron of the copper atom in compounds I and II is a distorted tetragonal pyramid. Obtained coordination compounds I and II exhibit antimicrobial and antifungal activities and have minimum inhibitory concentration and bactericidal concentration values in a range of 1.5-500 µg/mL. The study of the antioxidant activity shows that compounds I and II are less active than uncoordinated thiosemicarbazone H2L, but more active than trolox used in medical practice. |
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dc.description.sponsorship |
The work was performed within State Programs of the Republic of Moldova (projects 20.80009.5007.10 and 20.80009.5007.15). |
en |
dc.language.iso |
en |
en |
dc.subject |
Cu(II) complexes |
en |
dc.subject |
salicylaldehyde 4-allylthiosemicarbazone |
en |
dc.subject |
mixed-ligand amine-containing complexes |
en |
dc.subject |
antimicrobial |
en |
dc.subject |
antifungal |
en |
dc.subject |
and antioxidant activities |
en |
dc.title |
CRYSTAL STRUCTURES OF [N′-(2- OXIDOBENZYLIDENE)-N-(PROP-2-EN-1-YL)- CARBAMOHYDRAZONOTHIOATO(2-)](1,10- PHENANTHROLINE)COPPER AND [N′-(2- OXIDOBENZYLIDENE)-N-(PROP-2-EN-1-YL)- CARBAMOHYDRAZONOTHIOATO(2-)](2,2′- BIPYRIDINE)COPPER HEMIHYDRATES |
en |
dc.type |
Article |
en |