SUBSTITUTED 1,3-PHENYL(PYRIDYL) PROPENONES AND DERIVATIVES WITH THIOSEMICARBAZIDIC GROUPS. STRUCTRURE – (HL-60) ANTILEUKEMIA ACTIVITY RELATIONSHIP

Poirier, Donald; Popușoi, Ana; Roy, Jenny; Barba, Nicanor; Gulea, Aurelian

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dc.contributor.author	Popușoi, Ana
dc.contributor.author	Barba, Nicanor
dc.contributor.author	Gulea, Aurelian
dc.contributor.author	Roy, Jenny
dc.contributor.author	Poirier, Donald
dc.date.accessioned	2023-10-19T12:49:55Z
dc.date.available	2023-10-19T12:49:55Z
dc.date.issued	2014
dc.identifier.citation	POPUȘOI, Ana, GULEA, Aurelian, BARBA, Nicanor, ROY, Jenny, POIRIER, Donald. Substituted 1,3-phenyl (pyridyl) propenones and derivatives with thiosemicarbazidic groups. Structrure – (hl-60) antileukemia activity relationship. În: Chemistry Journal of Moldova, 2014, nr. 2(9), pp. 67-73. ISSN 1857-1727	en
dc.identifier.issn	1857-1727
dc.identifier.uri	http://dspace.usm.md:8080/xmlui/handle/123456789/11395
dc.identifier.uri	http://10.19261/cjm.2014.09(2).10
dc.description.abstract	3-(4-(Dimethylamino)phenyl-1-(4-isothiocyanatophenyl)prop-2-en-1-one was obtained from the corresponding N,N-dimethylthyoureas by elimination of dimethylamine at heating with gaseous hydrogen chloride in chloroform and 1-(4-isothiocyanatophenyl)-3-(pyridin-2-il)prop-2-en-1-one by treating 1,1-dimethyl-3-(4-(3-(pyridin-2-il)-acryloyl)-phenyl)thyourea with acetic anhydride. For all obtained compounds in the course of reaction the antileukemia activity was investigated.	en
dc.language.iso	en	en
dc.subject	chalcones	en
dc.subject	isothiocyanatopropenones	en
dc.subject	thioureas	en
dc.subject	antileukemia activity	en
dc.title	SUBSTITUTED 1,3-PHENYL(PYRIDYL) PROPENONES AND DERIVATIVES WITH THIOSEMICARBAZIDIC GROUPS. STRUCTRURE – (HL-60) ANTILEUKEMIA ACTIVITY RELATIONSHIP	en
dc.type	Article	en